Institute: University of Oxford
My work focusses on understanding the biology of typhoid infection, and the mechanisms by which vaccination confers protection from disease. Since Salmonella Typhi, the bacterium responsible for typhoid, exclusively infects humans, controlled human infection studies are an extremely valuable tool to study the disease and vaccine-mediated immunity.
My research interests include the role of natural killer cells in typhoid infection and immunological memory of NK cells, early responses to exposure to S. Typhi, Fc-mediated functional activities of typhoid-specific antibodies, and understanding cellular responses to vaccination and S. Typhi challenge through flow and mass cytometry.
A list of publications can be found here.
Web Links of Interest