Institute: KEM Hospital, Mumbai
I currently work as Professor (Additional) in the department of Clinical Pharmacology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai India. I began my career in the mid nineties with multi drug resistance Plasmodium falciparum malaria where I worked with both Indian and multinational pharmaceutical companies to test new drugs including the artemisinin derivatives. I subsequently worked in the area of filariasis investigating the safety and efficacy of Diethylcarbamazine versus Diethylcarbamazine + Albendazole in two villages in the state of Maharashtra with a high prevalence of malaria. I have also done work with multi drug resistant Plasmodium vivax malaria and worked on two Cochrane reviews for the use of artemisinin derivatives in P vivax malaria.
Over the last decade, our team has worked with several vaccines in all phases of drug development. Some of these include- a monoclonal antibody against rabies developed by the Serum Institute of India, meningitis, influenza, pneumococcal, rotavirus, Chikungunya vaccines and a hexavalent vaccine for childhood immunization. Other areas of interest include the use of pharmacogenetics to individualize drug therapy and we run the warfarin and clopidogrel clinics at the institute. The team has expertise in pharmacokinetics and we have worked with vancomycin and colistin in the intensive care unit to optimize anti- infective therapy in the critical care setting.
A list of publications can be found here.