Institute: Makerere University
Biography
I am a Pediatric Infectious Diseases specialist who has been working in the department of Paediatrics and Child Health, Makerere University and conducting research with the Makerere University-Johns Hopkins University research collaboration since 1995. I have conducted multiple perinatal HIV prevention clinical trials including HIVNET012 (Ugandan vice chair), single dose nevirapine (NVP) to mother and infant for prevention of mother to child HIV transmission, SWEN, and HPTN 046 (Ugandan site PI), extending infant NVP postpartum dosing to prevent breast milk transmission. In addition, we completed a Phase I HIV vaccine study to determine safety and immunogenicity of an ALVAC vaccine ( HPTN027). Most of these HIV prevention studies have contributed to the WHO guidelines for prevention of mother to child HIV transmission (PMTCT) in resource limited settings. In addition, I have been the PI for operational research to improve the postnatal follow up of HIV infected pregnant women enrolled in the PMTCT program in urban and rural health units. Over the last decade I have also conducted paediatric HIV treatment clinical trials to improve antiretroviral therapy for children in resource limited settings and paediatric TB diagnostics and treatment. I am committed to conducting research to identify interventions that prevent HIV infection in women, infants and their male partners, improve the treatment of HIV infected children and overall survival of children in resource limited settings. At the national level, I am the chair of the Ministry of Health, PMTCT and Paediatric ART technical committees.
Key Publications
A list of publications can be found here.
Web Links of Interest