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Resources and useful websites

News article "COVID-19 human challenge study reveals detailed insights into infection"

An animation to help explain how a human infection study can accelerate vaccine development.

An interview with Dr Chris Chiu, the doctor leading the human infection study with coronavirus

An interview with Jacob Hopkins, one of the first volunteers in the study

An article explaining how a human challenge study can help accelerate Covid-19 vaccines.

International registration of the screening protocol (to assess volunteers for their potential eligibility to participate in a dose finding human experimental infection study in healthy subjects using a GMP-produced SARS-CoV-2 wild type strain):

International registration of the first characterisation study

The WHO key criteria for ethical acceptability

WHO: Feasibility, potential value and limitations of establishing a closely monitored challenge model of experimental COVID-19 infection and illness in healthy young adult volunteers


Press releases:


Peer-reviewed publications:

SARS-CoV-2 Human Challenge Studies — Establishing the Model during an Evolving Pandemic

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults