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Resources and useful websites

Anyone considering volunteering for the human infection study with coronavirus can sign up here https://ukcovidchallenge.com/.

An animation https://youtu.be/FncT4ki-Uww to help explain how a human infection study can accelerate vaccine development.

An interview with Dr Chris Chiu, the doctor leading the human infection study with coronavirus https://soundcloud.com/user-499485249/infecting-people-with-covid-19.

An interview with Jacob Hopkins, one of the first volunteers in the study https://www.bbc.co.uk/news/av/uk-england-tyne-56893690.

An article explaining how a human challenge study can help accelerate Covid-19 vaccines.

International registration of the screening protocol (to assess volunteers for their potential eligibility to participate in a dose finding human experimental infection study in healthy subjects using a GMP-produced SARS-CoV-2 wild type strain):   https://clinicaltrials.gov/ct2/show/NCT04740320

International registration of the first characterisation study https://clinicaltrials.gov/ct2/show/NCT04865237

The WHO key criteria for ethical acceptability https://www.who.int/ethics/publications/key-criteria-ethical-acceptability-of-covid-19-human-challenge/en/

WHO: Feasibility, potential value and limitations of establishing a closely monitored challenge model of experimental COVID-19 infection and illness in healthy young adult volunteers https://www.who.int/publications/m/item/feasibility-potential-value-and-limitations-of-establishing-a-closely-monitored-challenge-model-of-experimental-covid-19-infection-and-illness-in-healthy-young-adult-volunteers

 

Press releases:

https://www.imperial.ac.uk/news/206893/uk-researchers-explore-human-challenge-studies/

https://www.imperial.ac.uk/news/215173/call-volunteers-worlds-first-coronavirus-human/

https://www.gov.uk/government/news/worlds-first-coronavirus-human-challenge-study-receives-ethics-approval-in-the-uk

https://www.imperial.ac.uk/news/218294/first-volunteers-covid-19-human-challenge-study/

https://www.ox.ac.uk/news/2021-04-19-human-challenge-trial-launches-study-immune-response-covid-19

https://otp.tools.investis.com/clients/uk/open_orphan/rns/regulatory-story.aspx?cid=2484&newsid=1474668